Projektsuche

GESUND - Reduction of intestinal colonization by multidrug-resistant foodborne pathogens in broiler chickens using targeted bacteriophage therapy

Authority

Niedersächsisches Ministerium für Ernährung, Landwirtschaft und Verbraucherschutz

Federal State

Lower Saxony and Hamburg

Contact

Calenberger Straße 2
30169 Hannover

Website: External link to the authority

Project Title

GESUND - Reduction of intestinal colonization by multidrug-resistant foodborne pathogens in broiler chickens using targeted bacteriophage therapy

Project description

The project aims to test the use of bacteriophages to reduce the colonization of poultry with MDR Enterobacteria and zoonotic pathogens, as well as the spread of MDR plasmids by bacteria. The use of phages as a non-antibiotic measure should be able to be integrated into existing hygiene concepts. On one hand, we will evaluate phages that are specific for important zoonotic pathogens like Campylobacter spp., and on the other hand, we will test phages that target receptors on Enterobacteria. With this approach, we could not only specifically kill MDR bacteria in the poultry gut, but also trigger the loss of MDR-encoding plasmids, leading to a return to antibiotic sensitivity in the intestinal bacteria. Using phage cocktails should help prevent the potential development of resistance in the bacterial target population. Furthermore, it’s being studied whether taking a probiotic by mouth at the same time can prevent pathogenic or resistant bacteria from settling in the gut after phage therapy, instead of the killed Enterobacteriaceae or Campylobacter.

Final report

Results and the Final report will be found here, as soon as the project is completed.

Keywords

Animal husbandry
Pest/disease control

Main funding source

Rural development 2023-2027 for Operational Groups (in the sense of Art 127 of Reg. 2021/2115)

OG contact information

Dr. Frieling Projekt- und Innovationsmanagement
Thomas-von-Aquin-Straße 10
49377 Vechta

Phone: 0163 567 4123

Email: info@frieling-solutions.com

Type of OG partners

Farmer
Advisor
Researcher
business in rural areas

Begin of project

2026

Project status

ongoing

Total budget applied for in EUR

474,774

NUTS3 CODE

DE94F